Drug repurposing for Mpox: Discovery of small molecules as potential inhibitors against DNA‐dependent RNA polymerase using molecular modeling approach

Mpox (formerly Monkeypox), a zoonotic illness caused by the Mpox virus, belongs to the Orthopoxvirus genus in the family Poxviridae. To design and develop effective antiviral therapeutics against DNA viruses, the DNA‐dependent RNA polymerase (DdRp) of poxviruses has emerged as a promising drug targe...

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Detalles Bibliográficos
Autores principales: Dutt, Mansi, Kumar, Anuj, Rout, Madhusmita, Dehury, Budheswar, Martinez, Gustavo, Ndishimye, Pacifique, Kelvin, Alyson A., Kelvin, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473176/
https://www.ncbi.nlm.nih.gov/pubmed/36946432
http://dx.doi.org/10.1002/jcb.30397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473176/
https://www.ncbi.nlm.nih.gov/pubmed/36946432
http://dx.doi.org/10.1002/jcb.30397

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