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Predicting longitudinal brain atrophy in Parkinson’s disease using a Susceptible-Infected-Removed agent-based model

Parkinson’s disease is a progressive neurodegenerative disorder characterized by accumulation of abnormal isoforms of alpha-synuclein. Alpha-synuclein is proposed to act as a prion in Parkinson’s disease: In its misfolded pathologic state, it favors the misfolding of normal alpha-synuclein molecules...

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Detalles Bibliográficos
Autores principales: Abdelgawad, Alaa, Rahayel, Shady, Zheng, Ying-Qiu, Tremblay, Christina, Vo, Andrew, Misic, Bratislav, Dagher, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MIT Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473281/
https://www.ncbi.nlm.nih.gov/pubmed/37781140
http://dx.doi.org/10.1162/netn_a_00296