Efficacy and Safety of Naloxegol in Patients with Chronic Non-Cancer Pain Who Experience Opioid-Induced Constipation: A Pooled Analysis of Two Global, Randomized Controlled Studies

OBJECTIVE: This study evaluates the onset, magnitude, and consistency of improvement of opioid-induced constipation (OIC) symptoms with naloxegol treatment. METHODS: This was a pooled analysis of two Phase 3, double-blind, randomized, placebo-controlled studies (KODIAC-04/05, NCT01309841/NCT01323790...

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Detalles Bibliográficos
Autores principales: Chey, William D, Brenner, Darren M, Cash, Brooks D, Hale, Martin, Adler, Jeremy, Jamindar, Mansi S, Rockett, Carol B, Almenoff, June S, Bortey, Enoch, Gudin, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473436/
https://www.ncbi.nlm.nih.gov/pubmed/37664485
http://dx.doi.org/10.2147/JPR.S417045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473436/
https://www.ncbi.nlm.nih.gov/pubmed/37664485
http://dx.doi.org/10.2147/JPR.S417045

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