SARS-CoV-2 nucleocapsid protein inhibits the PKR-mediated integrated stress response through RNA-binding domain N2b

The nucleocapsid protein N of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enwraps and condenses the viral genome for packaging but is also an antagonist of the innate antiviral defense. It suppresses the integrated stress response (ISR), purportedly by interacting with stress granul...

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Detalles Bibliográficos
Autores principales: Aloise, Chiara, Schipper, Jelle G., van Vliet, Arno, Oymans, Judith, Donselaar, Tim, Hurdiss, Daniel L., de Groot, Raoul J., van Kuppeveld, Frank J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473545/
https://www.ncbi.nlm.nih.gov/pubmed/37607209
http://dx.doi.org/10.1371/journal.ppat.1011582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473545/
https://www.ncbi.nlm.nih.gov/pubmed/37607209
http://dx.doi.org/10.1371/journal.ppat.1011582

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