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Mycobacterium tuberculosis response to cholesterol is integrated with environmental pH and potassium levels via a lipid utilization regulator

How bacterial response to environmental cues and nutritional sources may be integrated in enabling host colonization is poorly understood. Exploiting a reporter-based screen, we discovered that overexpression of Mycobacterium tuberculosis (Mtb) lipid utilization regulators altered Mtb acidic pH resp...

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Detalles Bibliográficos
Autores principales: Chen, Yue, MacGilvary, Nathan J., Tan, Shumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473576/
https://www.ncbi.nlm.nih.gov/pubmed/37662244
http://dx.doi.org/10.1101/2023.08.22.554309