Cargando…

Active learning of enhancer and silencer regulatory grammar in photoreceptors

Cis-regulatory elements (CREs) direct gene expression in health and disease, and models that can accurately predict their activities from DNA sequences are crucial for biomedicine. Deep learning represents one emerging strategy to model the regulatory grammar that relates CRE sequence to function. H...

Descripción completa

Detalles Bibliográficos
Autores principales: Friedman, Ryan Z., Ramu, Avinash, Lichtarge, Sara, Myers, Connie A., Granas, David M., Gause, Maria, Corbo, Joseph C., Cohen, Barak A., White, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473580/
https://www.ncbi.nlm.nih.gov/pubmed/37662358
http://dx.doi.org/10.1101/2023.08.21.554146