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Active learning of enhancer and silencer regulatory grammar in photoreceptors
Cis-regulatory elements (CREs) direct gene expression in health and disease, and models that can accurately predict their activities from DNA sequences are crucial for biomedicine. Deep learning represents one emerging strategy to model the regulatory grammar that relates CRE sequence to function. H...
Autores principales: | Friedman, Ryan Z., Ramu, Avinash, Lichtarge, Sara, Myers, Connie A., Granas, David M., Gause, Maria, Corbo, Joseph C., Cohen, Barak A., White, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473580/ https://www.ncbi.nlm.nih.gov/pubmed/37662358 http://dx.doi.org/10.1101/2023.08.21.554146 |
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