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Disrupted excitation-inhibition balance in cognitively normal individuals at risk of Alzheimer’s disease

BACKGROUND: Sex differences impact Alzheimer’s disease (AD) neuropathology, but cell-to-network level dysfunctions in the prodromal phase are unclear. Alterations in hippocampal excitation-inhibition balance (EIB) have recently been linked to early AD pathology. OBJECTIVE: Examine how AD risk factor...

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Detalles Bibliográficos
Autores principales: Fortel, Igor, Zhan., Liang, Ajilore., Olusola, Wu, Yichao, Mackin, Scott, Leow, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473582/
https://www.ncbi.nlm.nih.gov/pubmed/37662359
http://dx.doi.org/10.1101/2023.08.21.554061