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Analyse patient-level heterogeneity in Alzheimer’s Disease using multimodal normative modelling

BACKGROUND AND OBJECTIVES: Alzheimer’s disease (AD) is highly heterogenous, with significant variations in both clinical presentation and neurobiology. To explore this, we used normative modelling on multimodal neuroimaging data to index spatial patterns of neuroanatomical and neuropathological vari...

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Detalles Bibliográficos
Autores principales: Kumar, Sayantan, Earnest, Thomas, Payne, Philip R.O., Sotiras, Aristeidis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473626/
https://www.ncbi.nlm.nih.gov/pubmed/37662280
http://dx.doi.org/10.1101/2023.08.15.553412