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Analysis of Pseudomonas aeruginosa transcription in an ex vivo cystic fibrosis sputum model identifies metal restriction as a gene expression stimulus

Chronic Pseudomonas aeruginosa lung infections are a distinctive feature of cystic fibrosis (CF) pathology, that challenge adults with CF even with the advent of highly effective modulator therapies. Characterizing P. aeruginosa transcription in the CF lung and identifying factors that drive gene ex...

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Detalles Bibliográficos
Autores principales: Neff, Samuel L., Doing, Georgia, Reiter, Taylor, Hampton, Thomas H., Greene, Casey S., Hogan, Deborah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473638/
https://www.ncbi.nlm.nih.gov/pubmed/37662412
http://dx.doi.org/10.1101/2023.08.21.554169