Deep screening of proximal and distal splicing-regulatory elements in a native sequence context

Pre-mRNA splicing, a key process in gene expression, can be therapeutically modulated using various drug modalities, including antisense oligonucleotides (ASOs). However, determining promising targets is impeded by the challenge of systematically mapping splicing-regulatory elements (SREs) in their...

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Detalles Bibliográficos
Autores principales: Recinos, Yocelyn, Ustianenko, Dmytro, Yeh, Yow-Tyng, Wang, Xiaojian, Jacko, Martin, Yesantharao, Lekha V., Wu, Qiyang, Zhang, Chaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473672/
https://www.ncbi.nlm.nih.gov/pubmed/37662340
http://dx.doi.org/10.1101/2023.08.21.554109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473672/
https://www.ncbi.nlm.nih.gov/pubmed/37662340
http://dx.doi.org/10.1101/2023.08.21.554109

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