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Accurate Simulation of Coupling between Protein Secondary Structure and Liquid-Liquid Phase Separation

Intrinsically disordered proteins (IDPs) frequently mediate liquid-liquid phase separation (LLPS) that underlies the formation of membraneless organelles. Together with theory and experiment, efficient coarse-grained (CG) simulations have been instrumental in understanding sequence-specific phase se...

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Detalles Bibliográficos
Autores principales: Zhang, Yumeng, Li, Shanlong, Gong, Xiping, Chen, Jianhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473686/
https://www.ncbi.nlm.nih.gov/pubmed/37662293
http://dx.doi.org/10.1101/2023.08.22.554378