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Accurate Simulation of Coupling between Protein Secondary Structure and Liquid-Liquid Phase Separation
Intrinsically disordered proteins (IDPs) frequently mediate liquid-liquid phase separation (LLPS) that underlies the formation of membraneless organelles. Together with theory and experiment, efficient coarse-grained (CG) simulations have been instrumental in understanding sequence-specific phase se...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473686/ https://www.ncbi.nlm.nih.gov/pubmed/37662293 http://dx.doi.org/10.1101/2023.08.22.554378 |