Nitric Oxide modulates spontaneous Ca(2+) release and ventricular arrhythmias during β-adrenergic signalling through S-nitrosylation of Calcium/Calmodulin dependent kinase II

RATIONALE: Nitric oxide (NO) has been identified as a signalling molecule generated during β-adrenergic receptor (AR) stimulation in the heart. Furthermore, a role for NO in triggering spontaneous Ca(2+) release via S-nitrosylation of Ca(2+)/calmodulin kinase II delta (CaMKIIδ) is emerging. NO donor...

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Detalles Bibliográficos
Autores principales: Power, Amelia S., Asamudo, Esther, Worthington, Luke P. I., Alim, Chidera C., Parackal, Raquel, Wallace, Rachel S., Ebenebe, Obialunanma V., Brown, Joan Heller, Kohr, Mark J., Bers, Donald M., Erickson, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473710/
https://www.ncbi.nlm.nih.gov/pubmed/37662205
http://dx.doi.org/10.1101/2023.08.23.554546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473710/
https://www.ncbi.nlm.nih.gov/pubmed/37662205
http://dx.doi.org/10.1101/2023.08.23.554546

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