α-catenin mechanosensitivity as a route to cytokinesis failure through sequestration of LZTS2

Epithelial cells can become polyploid upon tissue injury, but mechanosensitive cues that trigger this state are poorly understood. Using α-catenin (α-cat) knock-out Madin Darby Canine Kidney (MDCK) cells reconstituted with wild-type and mutant forms of α-cat as a model system, we find that an establ...

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Detalles Bibliográficos
Autores principales: Wang, Yuou, Yemelyanov, Alex, Go, Christopher D., Kim, Sun, Quinn, Jeanne M., Flozak, Annette S., Le, Phuong M., Liang, Shannon, Claude-Gingras, Anne, Ikura, Mitsu, Ishiyama, Noboru, Gottardi, Cara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473746/
https://www.ncbi.nlm.nih.gov/pubmed/37662204
http://dx.doi.org/10.1101/2023.08.25.554884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473746/
https://www.ncbi.nlm.nih.gov/pubmed/37662204
http://dx.doi.org/10.1101/2023.08.25.554884

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