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Higher-Order Dynamics Beyond Repolarization Alternans in Ex-Vivo Human Ventricles are Independent of the Restitution Properties

BACKGROUND: Repolarization alternans, defined as period-2 oscillation in the repolarization phase of the action potentials, provides a mechanistic link between cellular dynamics and ventricular fibrillation (VF). Theoretically, higher-order periodicities (e.g., periods 4, 6, 8,...) are expected but...

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Detalles Bibliográficos
Autores principales: Iravanian, Shahriar, Uzelac, Ilija, Shah, Anand D, Toye, Mikael J, Lloyd, Michael S., Burke, Michael A., Daneshmand, Mani A, Attia, Tamer S, Vega, J David, El-Chami, Michael, Merchant, Faisal M., Cherry, Elizabeth M, Bhatia, Neal K., Fenton, Flavio H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473769/
https://www.ncbi.nlm.nih.gov/pubmed/37662394
http://dx.doi.org/10.1101/2023.08.16.23293853