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Higher-Order Dynamics Beyond Repolarization Alternans in Ex-Vivo Human Ventricles are Independent of the Restitution Properties
BACKGROUND: Repolarization alternans, defined as period-2 oscillation in the repolarization phase of the action potentials, provides a mechanistic link between cellular dynamics and ventricular fibrillation (VF). Theoretically, higher-order periodicities (e.g., periods 4, 6, 8,...) are expected but...
Autores principales: | Iravanian, Shahriar, Uzelac, Ilija, Shah, Anand D, Toye, Mikael J, Lloyd, Michael S., Burke, Michael A., Daneshmand, Mani A, Attia, Tamer S, Vega, J David, El-Chami, Michael, Merchant, Faisal M., Cherry, Elizabeth M, Bhatia, Neal K., Fenton, Flavio H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473769/ https://www.ncbi.nlm.nih.gov/pubmed/37662394 http://dx.doi.org/10.1101/2023.08.16.23293853 |
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