The combined effect of lifestyle factors and polygenic scores on age at onset in Parkinson’s disease

OBJECTIVE: To investigate the association between a Parkinson’s disease (PD)-specific polygenic score (PGS) and protective lifestyle factors on age at onset (AAO) in PD. METHODS: We included data from 4375 patients with idiopathic PD, 167 patients with GBA1-PD, and 3091 healthy controls of European...

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Detalles Bibliográficos
Autores principales: Gabbert, Carolin, Blöbaum, Leonie, Lüth, Theresa, König, Inke R., Caliebe, Amke, Koch, Sebastian, Björn-Hergen, Laabs, Klein, Christine, Trinh, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473779/
https://www.ncbi.nlm.nih.gov/pubmed/37662355
http://dx.doi.org/10.1101/2023.08.25.23294466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473779/
https://www.ncbi.nlm.nih.gov/pubmed/37662355
http://dx.doi.org/10.1101/2023.08.25.23294466

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