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AORTA Gene: Polygenic prediction improves detection of thoracic aortic aneurysm

BACKGROUND: Thoracic aortic disease is an important cause of morbidity and mortality in the US, and aortic diameter is a heritable contributor to risk. Could a polygenic prediction of ascending aortic diameter improve detection of aortic aneurysm? METHODS: Deep learning was used to measure ascending...

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Detalles Bibliográficos
Autores principales: Pirruccello, James P., Khurshid, Shaan, Lin, Honghuang, Lu-Chen, Weng, Zamirpour, Siavash, Kany, Shinwan, Raghavan, Avanthi, Koyama, Satoshi, Vasan, Ramachandran S., Benjamin, Emelia J., Lindsay, Mark E., Ellinor, Patrick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473783/
https://www.ncbi.nlm.nih.gov/pubmed/37662232
http://dx.doi.org/10.1101/2023.08.23.23294513