Fracture healing in a polytrauma rat model is influenced by mtDNA:cGAS complex mediated pro-inflammation

PURPOSE: The mitochondrial DNA (mtDNA) activated cyclic guanosine monophosphate–adenosine monophosphate synthase—stimulator of interferon genes (cGAS-STING) signaling pathway is a key player in mediating immune responses in autoimmune disorders and cancer. However, its role in severe trauma associat...

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Detalles Bibliográficos
Autores principales: Muire, Preeti J., Lofgren, Alicia L., Shiels, Stefanie M., Wenke, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473996/
https://www.ncbi.nlm.nih.gov/pubmed/37656236
http://dx.doi.org/10.1186/s40634-023-00637-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473996/
https://www.ncbi.nlm.nih.gov/pubmed/37656236
http://dx.doi.org/10.1186/s40634-023-00637-5

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