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Fracture healing in a polytrauma rat model is influenced by mtDNA:cGAS complex mediated pro-inflammation
PURPOSE: The mitochondrial DNA (mtDNA) activated cyclic guanosine monophosphate–adenosine monophosphate synthase—stimulator of interferon genes (cGAS-STING) signaling pathway is a key player in mediating immune responses in autoimmune disorders and cancer. However, its role in severe trauma associat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473996/ https://www.ncbi.nlm.nih.gov/pubmed/37656236 http://dx.doi.org/10.1186/s40634-023-00637-5 |