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Revealing polygenic pleiotropy using genetic risk scores for asthma
In this study we examined how genetic risk for asthma associates with different features of the disease and with other medical conditions and traits. Using summary statistics from two multi-ancestry genome-wide association studies of asthma, we modeled polygenic risk scores (PRSs) and validated thei...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474095/ https://www.ncbi.nlm.nih.gov/pubmed/37663543 http://dx.doi.org/10.1016/j.xhgg.2023.100233 |