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Revealing polygenic pleiotropy using genetic risk scores for asthma

In this study we examined how genetic risk for asthma associates with different features of the disease and with other medical conditions and traits. Using summary statistics from two multi-ancestry genome-wide association studies of asthma, we modeled polygenic risk scores (PRSs) and validated thei...

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Detalles Bibliográficos
Autores principales:	Dapas, Matthew, Lee, Yu Lin, Wentworth-Sheilds, William, Im, Hae Kyung, Ober, Carole, Schoettler, Nathan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474095/ https://www.ncbi.nlm.nih.gov/pubmed/37663543 http://dx.doi.org/10.1016/j.xhgg.2023.100233

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