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CARM1 arginine methyltransferase as a therapeutic target for cancer

Coactivator-associated arginine methyltransferase 1 (CARM1) is an arginine methyltransferase that posttranslationally modifies proteins that regulate multiple levels of RNA production and processing. Its substrates include histones, transcription factors, coregulators of transcription, and splicing...

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Detalles Bibliográficos
Autores principales: Santos, Margarida, Hwang, Jee Won, Bedford, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474102/
https://www.ncbi.nlm.nih.gov/pubmed/37536629
http://dx.doi.org/10.1016/j.jbc.2023.105124