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TGR5 supresses cGAS/STING pathway by inhibiting GRP75-mediated endoplasmic reticulum-mitochondrial coupling in diabetic retinopathy

Diabetic retinopathy (DR) is a serious and relatively under-recognized complication of diabetes. Müller glial cells extend throughout the retina and play vital roles in maintaining retinal homeostasis. Previous studies have demonstrated that TGR5, a member of the bile acid-activated GPCR family, cou...

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Detalles Bibliográficos
Autores principales:	Li, Yan, Zhu, Lingpeng, Cai, Meng-Xia, Wang, Zi-Li, Zhuang, Miao, Tan, Cheng-Ye, Xie, Tian-Hua, Yao, Yong, Wei, Ting-Ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474119/ https://www.ncbi.nlm.nih.gov/pubmed/37658045 http://dx.doi.org/10.1038/s41419-023-06111-5

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