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Computational immunohistochemical mapping adds immune context to histological phenotypes in mouse models of colitis

Inflammatory bowel disease (IBD) is characterized by chronic, dysregulated inflammation in the gastrointestinal tract. The heterogeneity of IBD is reflected through two major subtypes, Crohn’s Disease (CD) and Ulcerative Colitis (UC). CD and UC differ across symptomatic presentation, histology, immu...

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Detalles Bibliográficos
Autores principales: Kobayashi, Soma, Sullivan, Christopher, Bialkowska, Agnieszka B., Saltz, Joel H., Yang, Vincent W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474139/
https://www.ncbi.nlm.nih.gov/pubmed/37658187
http://dx.doi.org/10.1038/s41598-023-41574-8