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Three-dimensional growth sensitizes breast cancer cells to treatment with ferroptosis-promoting drugs

Drugs causing ferroptosis, iron-mediated cell death, represent promising tools for cancer treatment. While exploring the effect of these drugs on breast cancer (BC), we found that a ferroptosis-inducing drug erastin dramatically inhibits tumorigenicity of human BC cells in mice but when used at a co...

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Detalles Bibliográficos
Autores principales: Chipurupalli, Sandhya, Jiang, Peijia, Liu, Xiaoyang, Santos, Julia Linhares, Marcato, Paola, Rosen, Kirill V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474142/
https://www.ncbi.nlm.nih.gov/pubmed/37658069
http://dx.doi.org/10.1038/s41419-023-06106-2