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Pro-arrhythmic effect of escitalopram and citalopram at serum concentrations commonly observed in older patients – a study based on a cohort of 19,742 patients

BACKGROUND: For a decade, patients have been advised against using high citalopram- and escitalopram-doses due to risk for ventricular arrhythmia and cardiac arrest. Still, these drugs are widely used to treat depression and anxiety especially in older patients. It is unclear why they are cardiotoxi...

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Detalles Bibliográficos
Autores principales: Faraj, Pari, Størset, Elisabet, Hole, Kristine, Smith, Godfrey, Molden, Espen, Dietrichs, Erik Sveberg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474154/
https://www.ncbi.nlm.nih.gov/pubmed/37639937
http://dx.doi.org/10.1016/j.ebiom.2023.104779