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ALKBH5 facilitates CYP1B1 mRNA degradation via m6A demethylation to alleviate MSC senescence and osteoarthritis progression

Improving health and delaying aging is the focus of medical research. Previous studies have shown that mesenchymal stem cell (MSC) senescence is closely related to organic aging and the development of aging-related diseases such as osteoarthritis (OA). m6A is a common RNA modification that plays an...

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Detalles Bibliográficos
Autores principales: Ye, Guiwen, Li, Jinteng, Yu, Wenhui, Xie, Zhongyu, Zheng, Guan, Liu, Wenjie, Wang, Shan, Cao, Qian, Lin, Jiajie, Su, Zepeng, Li, Dateng, Che, Yunshu, Fan, Shuai, Wang, Peng, Wu, Yanfeng, Shen, Huiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474288/
https://www.ncbi.nlm.nih.gov/pubmed/37524872
http://dx.doi.org/10.1038/s12276-023-01059-0