Cargando…

Theranostic approach to specifically targeting the interloop region of BCL2 i-motif DNA by crystal violet

Ligands that recognise specific i-motif DNAs are helpful in cancer diagnostics and therapeutics, as i-motif formation can cause cancer. Although the loop regions of i-motifs are promising targets for ligands, the interaction between a ligand and the loop regions based on sequence information remains...

Descripción completa

Detalles Bibliográficos
Autores principales: Das, Sinjan, Takahashi, Shuntaro, Ohyama, Tatsuya, Bhowmik, Sudipta, Sugimoto, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474294/
https://www.ncbi.nlm.nih.gov/pubmed/37658102
http://dx.doi.org/10.1038/s41598-023-39407-9