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Transposable elements as tissue-specific enhancers in cancers of endodermal lineage

Transposable elements (TE) are repetitive genomic elements that harbor binding sites for human transcription factors (TF). A regulatory role for TEs has been suggested in embryonal development and diseases such as cancer but systematic investigation of their functions has been limited by their wides...

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Detalles Bibliográficos
Autores principales: Karttunen, Konsta, Patel, Divyesh, Xia, Jihan, Fei, Liangru, Palin, Kimmo, Aaltonen, Lauri, Sahu, Biswajyoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474299/
https://www.ncbi.nlm.nih.gov/pubmed/37658059
http://dx.doi.org/10.1038/s41467-023-41081-4