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α,α-disubstituted β-amino amides eliminate Staphylococcus aureus biofilms by membrane disruption and biomass removal

Bacterial biofilms account for up to 80% of all infections and complicate successful therapies due to their intrinsic tolerance to antibiotics. Biofilms also cause serious problems in the industrial sectors, for instance due to the deterioration of metals or microbial contamination of products. Effo...

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Detalles Bibliográficos
Autores principales: Ausbacher, Dominik, Miller, Lindsey A., Goeres, Darla M., Stewart, Philip S., Strøm, Morten B., Fallarero, Adyary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474319/
https://www.ncbi.nlm.nih.gov/pubmed/37662850
http://dx.doi.org/10.1016/j.bioflm.2023.100151