Discovering the mechanism of action of drugs with a sparse explainable network

BACKGROUND: Although Deep Neural Networks (DDNs) have been successful in predicting the efficacy of cancer drugs, the lack of explainability in their decision-making process is a significant challenge. Previous research proposed mimicking the Gene Ontology structure to allow for interpretation of ea...

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Detalles Bibliográficos
Autores principales: Sada Del Real, Katyna, Rubio, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474372/
https://www.ncbi.nlm.nih.gov/pubmed/37633093
http://dx.doi.org/10.1016/j.ebiom.2023.104767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474372/
https://www.ncbi.nlm.nih.gov/pubmed/37633093
http://dx.doi.org/10.1016/j.ebiom.2023.104767

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