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Discovering the mechanism of action of drugs with a sparse explainable network
BACKGROUND: Although Deep Neural Networks (DDNs) have been successful in predicting the efficacy of cancer drugs, the lack of explainability in their decision-making process is a significant challenge. Previous research proposed mimicking the Gene Ontology structure to allow for interpretation of ea...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474372/ https://www.ncbi.nlm.nih.gov/pubmed/37633093 http://dx.doi.org/10.1016/j.ebiom.2023.104767 |