Combating pan-coronavirus infection by indomethacin through simultaneously inhibiting viral replication and inflammatory response

Severe infections with coronaviruses are often accompanied with hyperinflammation, requiring therapeutic strategies to simultaneously tackle the virus and inflammation. By screening a safe-in-human broad-spectrum antiviral agents library, we identified that indomethacin can inhibit pan-coronavirus i...

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Detalles Bibliográficos
Autores principales: Wang, Yining, Li, Pengfei, Xu, Lei, de Vries, Annemarie C., Rottier, Robbert J., Wang, Wenshi, Crombag, Marie-Rose B.S., Peppelenbosch, Maikel P., Kainov, Denis E., Pan, Qiuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474465/
https://www.ncbi.nlm.nih.gov/pubmed/37664584
http://dx.doi.org/10.1016/j.isci.2023.107631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474465/
https://www.ncbi.nlm.nih.gov/pubmed/37664584
http://dx.doi.org/10.1016/j.isci.2023.107631

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