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A riboside hydrolase that salvages both nucleobases and nicotinamide in the auxotrophic parasite Trichomonas vaginalis

Pathogenic parasites of the Trichomonas genus are causative agents of sexually transmitted diseases affecting millions of individuals worldwide and whose outcome may include stillbirths and enhanced cancer risks and susceptibility to HIV infection. Trichomonas vaginalis relies on imported purine and...

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Detalles Bibliográficos
Autores principales: Patrone, Marco, Galasyn, Gregory S., Kerin, Fiona, Nyitray, Mattias M., Parkin, David W., Stockman, Brian J., Degano, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474468/
https://www.ncbi.nlm.nih.gov/pubmed/37482279
http://dx.doi.org/10.1016/j.jbc.2023.105077