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ShlA toxin of Serratia induces P2Y2- and α5β1-dependent autophagy and bacterial clearance from host cells

Serratia marcescens is an opportunistic human pathogen involved in antibiotic-resistant hospital acquired infections. Upon contact with the host epithelial cell and prior to internalization, Serratia induces an early autophagic response that is entirely dependent on the ShlA toxin. Once Serratia inv...

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Detalles Bibliográficos
Autores principales: Tuttobene, Marisel R., Schachter, Julieta, Álvarez, Cora L., Saffioti, Nicolás A., Leal Denis, M. Florencia, Kessler, Horst, García Véscovi, Eleonora, Schwarzbaum, Pablo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474472/
https://www.ncbi.nlm.nih.gov/pubmed/37527778
http://dx.doi.org/10.1016/j.jbc.2023.105119