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FBXW7 in breast cancer: mechanism of action and therapeutic potential

Breast cancer is one of the frequent tumors that seriously endanger the physical and mental well-being in women. F-box and WD repeat domain-containing 7 (FBXW7) is a neoplastic repressor. Serving as a substrate recognition element for ubiquitin ligase, FBXW7 participates in the ubiquitin–proteasome...

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Detalles Bibliográficos
Autores principales: Chen, Siyu, Leng, Ping, Guo, Jinlin, Zhou, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474666/
https://www.ncbi.nlm.nih.gov/pubmed/37658431
http://dx.doi.org/10.1186/s13046-023-02767-1