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Does the addition of metformin to carboplatin treatment decreases ovarian reserve damage associated with carboplatin usage?

BACKGROUND: We aimed to determine whether adding metformin to carboplatin treatment would reduce the damage to ovarian reserve associated with carboplatin use. METHODS: We included 35 adult female non-pregnant albino Wistar rats approximately three months old, weighing 220–310 g. The rats were divid...

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Detalles Bibliográficos
Autores principales: Ayhan, Sevgi, Hancerliogullari, Necati, Guney, Gurhan, Gozukucuk, Murat, Caydere, Muzaffer, Guney, Sergul Selvi, Tokmak, Aytekin, Ustun, Yusuf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474675/
https://www.ncbi.nlm.nih.gov/pubmed/37660125
http://dx.doi.org/10.1186/s13048-023-01259-2