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Atorvastatin rescues hyperhomocysteinemia-induced cognitive deficits and neuroinflammatory gene changes

BACKGROUND: Epidemiological data suggests statins could reduce the risk of dementia, and more specifically, Alzheimer’s disease (AD). Pre-clinical data suggests statins reduce the risk of dementia through their pleiotropic effects rather than their cholesterol lowering effects. While AD is a leading...

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Detalles Bibliográficos
Autores principales: Weekman, Erica M., Johnson, Sherika N., Rogers, Colin B., Sudduth, Tiffany L., Xie, Kevin, Qiao, Qi, Fardo, David W., Bottiglieri, Teodoro, Wilcock, Donna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474691/
https://www.ncbi.nlm.nih.gov/pubmed/37658433
http://dx.doi.org/10.1186/s12974-023-02883-x