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Atorvastatin rescues hyperhomocysteinemia-induced cognitive deficits and neuroinflammatory gene changes
BACKGROUND: Epidemiological data suggests statins could reduce the risk of dementia, and more specifically, Alzheimer’s disease (AD). Pre-clinical data suggests statins reduce the risk of dementia through their pleiotropic effects rather than their cholesterol lowering effects. While AD is a leading...
Autores principales: | Weekman, Erica M., Johnson, Sherika N., Rogers, Colin B., Sudduth, Tiffany L., Xie, Kevin, Qiao, Qi, Fardo, David W., Bottiglieri, Teodoro, Wilcock, Donna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474691/ https://www.ncbi.nlm.nih.gov/pubmed/37658433 http://dx.doi.org/10.1186/s12974-023-02883-x |
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