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The Pro-Tumor Biological Function of IL-36α Plays an Important Role in the Tumor Microenvironment of HCC

PURPOSE: To investigate the role of IL-36 in the tumorigenesis of hepatocellular carcinoma (HCC). IL-36 composed of a natural antagonist (IL-36Ra) and three agonists (IL-36α, -β, -γ) that stimulate inflammation by binding to a common receptor consisting of IL-36R and IL-1RAcP. HCC is a common malign...

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Detalles Bibliográficos
Autores principales: Song, Yanmei, Chu, Huiyuan, Liu, Fang, Guo, Wenjie, Gao, Na, Chen, Che, Bao, Shisan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474893/
https://www.ncbi.nlm.nih.gov/pubmed/37663894
http://dx.doi.org/10.2147/CMAR.S407123