The Future Glioblastoma Clinical Trials Landscape: Early Phase 0, Window of Opportunity, and Adaptive Phase I–III Studies

PURPOSE OF REVIEW: Innovative clinical trial designs for glioblastoma (GBM) are needed to expedite drug discovery. Phase 0, window of opportunity, and adaptive designs have been proposed, but their advanced methodologies and underlying biostatistics are not widely known. This review summarizes phase...

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Detalles Bibliográficos
Autores principales: Cho, Nicholas S., Wong, Weng Kee, Nghiemphu, Phioanh L., Cloughesy, Timothy F., Ellingson, Benjamin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474988/
https://www.ncbi.nlm.nih.gov/pubmed/37402043
http://dx.doi.org/10.1007/s11912-023-01433-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474988/
https://www.ncbi.nlm.nih.gov/pubmed/37402043
http://dx.doi.org/10.1007/s11912-023-01433-1

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