Uncertainty assessment of proarrhythmia predictions derived from multi-level in silico models

In silico methods can be used for an early assessment of arrhythmogenic properties of drug candidates. However, their use for decision-making is conditioned by the possibility to estimate the predictions’ uncertainty. This work describes our efforts to develop uncertainty quantification methods for...

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Detalles Bibliográficos
Autores principales: Kopańska, Karolina, Rodríguez-Belenguer, Pablo, Llopis-Lorente, Jordi, Trenor, Beatriz, Saiz, Javier, Pastor, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
In Silico
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474996/
https://www.ncbi.nlm.nih.gov/pubmed/37528229
http://dx.doi.org/10.1007/s00204-023-03557-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10474996/
https://www.ncbi.nlm.nih.gov/pubmed/37528229
http://dx.doi.org/10.1007/s00204-023-03557-6

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