Quantitation and integrity evaluation of RNA genome in lentiviral vectors by direct reverse transcription-droplet digital PCR (direct RT-ddPCR)

Lentiviral vectors (LV) have proven to be powerful tools for stable gene delivery in both dividing and non-dividing cells. Approval of these LVs for use in clinical applications has been achieved by improvements in LV design. Critically important characteristics concerning quality control are LV tit...

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Detalles Bibliográficos
Autores principales: He, Zhiyong, Kwee, Edward J., Cleveland, Megan H., Cole, Kenneth D., Lin-Gibson, Sheng, He, Hua-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475045/
https://www.ncbi.nlm.nih.gov/pubmed/37660227
http://dx.doi.org/10.1038/s41598-023-41644-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475045/
https://www.ncbi.nlm.nih.gov/pubmed/37660227
http://dx.doi.org/10.1038/s41598-023-41644-x

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