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Quantitation and integrity evaluation of RNA genome in lentiviral vectors by direct reverse transcription-droplet digital PCR (direct RT-ddPCR)
Lentiviral vectors (LV) have proven to be powerful tools for stable gene delivery in both dividing and non-dividing cells. Approval of these LVs for use in clinical applications has been achieved by improvements in LV design. Critically important characteristics concerning quality control are LV tit...
Autores principales: | He, Zhiyong, Kwee, Edward J., Cleveland, Megan H., Cole, Kenneth D., Lin-Gibson, Sheng, He, Hua-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475045/ https://www.ncbi.nlm.nih.gov/pubmed/37660227 http://dx.doi.org/10.1038/s41598-023-41644-x |
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