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Structure based virtual screening and molecular simulation study of FDA-approved drugs to inhibit human HDAC6 and VISTA as dual cancer immunotherapy

Cancer immunotherapy has significantly contributed to the treatment of various types of cancers mainly by targeting immune checkpoint inhibitors (ICI). Among them, V-domain immunoglobulin suppressor of T cell activation (VISTA) has been explored as a promising therapeutic target. Besides, histone de...

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Detalles Bibliográficos
Autores principales: Shahab, Muhammad, Al-Madhagi, Haitham, Zheng, Guojun, Zeb, Amir, Alasmari, Abdullah Fayez, Alharbi, Metab, Alasmari, Fawaz, Khan, Muhammad Qayash, Khan, Momin, Wadood, Abdul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475047/
https://www.ncbi.nlm.nih.gov/pubmed/37660065
http://dx.doi.org/10.1038/s41598-023-41325-9