Structure-based design of a strain transcending AMA1-RON2L malaria vaccine

Apical membrane antigen 1 (AMA1) is a key malaria vaccine candidate and target of neutralizing antibodies. AMA1 binds to a loop in rhoptry neck protein 2 (RON2L) to form the moving junction during parasite invasion of host cells, and this complex is conserved among apicomplexan parasites. AMA1-RON2L...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Palak N., Dickey, Thayne H., Diouf, Ababacar, Salinas, Nichole D., McAleese, Holly, Ouahes, Tarik, Long, Carole A., Miura, Kazutoyo, Lambert, Lynn E., Tolia, Niraj H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475129/
https://www.ncbi.nlm.nih.gov/pubmed/37660103
http://dx.doi.org/10.1038/s41467-023-40878-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475129/
https://www.ncbi.nlm.nih.gov/pubmed/37660103
http://dx.doi.org/10.1038/s41467-023-40878-7

Ejemplares similares