TNFα induced by DNA-sensing in macrophage compromises retinal pigment epithelial (RPE) barrier function

Increasing evidence suggests that chronic inflammation plays an important role in the pathogenesis of age-related macular degeneration (AMD); however, the precise pathogenic stressors and sensors, and their impact on disease progression remain unclear. Several studies have demonstrated that type I i...

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Detalles Bibliográficos
Autores principales: Twarog, Michael, Schustak, Joshua, Xu, YongYao, Coble, Matthew, Dolan, Katie, Esterberg, Robert, Huang, Qian, Saint-Geniez, Magali, Bao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475136/
https://www.ncbi.nlm.nih.gov/pubmed/37660150
http://dx.doi.org/10.1038/s41598-023-41610-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475136/
https://www.ncbi.nlm.nih.gov/pubmed/37660150
http://dx.doi.org/10.1038/s41598-023-41610-7

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