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Mesenchymal-derived extracellular vesicles enhance microglia-mediated synapse remodeling after cortical injury in aging Rhesus monkeys

Understanding the microglial neuro-immune interactions in the primate brain is vital to developing therapeutics for cortical injury, such as stroke or traumatic brain injury. Our previous work showed that mesenchymal-derived extracellular vesicles (MSC-EVs) enhanced motor recovery in aged rhesus mon...

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Detalles Bibliográficos
Autores principales: Zhou, Yuxin, Bhatt, Hrishti, Mojica, Chromewell A., Xin, Hongqi, Pessina, Monica A., Rosene, Douglas L., Moore, Tara L., Medalla, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475204/
https://www.ncbi.nlm.nih.gov/pubmed/37660145
http://dx.doi.org/10.1186/s12974-023-02880-0